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Within a modern study, we noted the identification as well as characterization of a fresh atypical opioid receptor with distinctive unfavorable regulatory properties toward opioid peptides.1 Our results confirmed that ACKR3/CXCR7, hitherto often called an atypical scavenger receptor for chemokines CXCL12 and CXCL11, can also be a broad-spectrum sca